ethylene glycol monobutyl ether health effects

A U.S. … The available information on the acute and subchronic toxicity of ethylene glycol monobutyl ether is reviewed. Ethylene Glycol Monobutyl Ether; Community Right-To-Know Toxic Chemical Release Reporting, 60818-60825 [2015-25674] DIPROPYLENE GLYCOL BUTYL ETHER can be found in 39 products. Office of Pesticide Programs Pesticide Chemical Search. 3 Independent Consultant. Acute toxicity: Oral: Harmful if swallowed. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. Substance name : Glycol Ether EB CAS-No. Toxicol Appl Pharmacol. The acute and subehronic toxicity of EGEE, EGPE and EGBE was reviewed by C. C. Conaway (Texaco, In this document, NIOSH recommends occupational exposure limits for ethylene glycol monobutyl ether (EGBE) and its acetate, ethylene glycol monobutyl ether acetate (EGBEA). This substance ranges from B to C depending on concentration/usage. The publication also examines the occupational health risks of exposure to these chemicals and presents criteria for eliminating or minimizing these risks during the manufacture and use of EGBE and EGBEA. In evaluating the hazard that this chemical … Ethylene glycol monobutyl ether has also been tested for teratogenldty … 1984 Aug;57:75-84. doi: 10.1289/ehp.845775. GENERIC NAME(S): Carbitol (Bulk) ... You may report side effects to Health Canada at 1-866-234-2345. Studies on ethylene glycol alkyl ethers and related compounds … Gaschromatographic determination of butoxyacetic acid after hydrolysis of conjugated metabolites in urine from workers exposed to 2-butoxyethanol. -, Nature. Diethylene glycol ethers were absorbed more slowly than the corresponding ethylene glycol ethers. Chemical Name. Epub 2017 Jun 26. Toxicological Review of Ethylene Glycol Monobutyl Ether (EGBE) (CAS No. Chronic exposure in humans is associated with neurological and blood effects, such as nausea, tremor, and anemia. Occupational Exposure to Ethylene Glycol Monobutyl Ether and Ethylene Glycol Monobutyl Ether Acetate. Where is it found and how is it used? 4.3.  |  EPA has denied a petition to remove Ethylene Glycol Monobutyl Ether ... toxicity data for EGBE and concluded that it can reasonably be anticipated to cause serious or irreversible chronic health effects in humans, specifically, liver toxicity and concerns for hematological effects. Another group of 121 lamination workers with indirect exposure to EGME was recruited as the control group. It is a colorless, practically odorless, poisonous, and hygroscopic liquid with a sweetish taste. 0.03ppm; P=0.017). Studies on EGM using hamsters or guinea pigs revealed the occurrence of testicular atrophy similar to that observed in mice. Precautions. Ethylene Glycol Monobutyl Ether 111-76-2 <25 * *The exact percentage (concentration) of composition has been withheld as a trade secret. DEG is a widely used solvent. For this reason, some items on this page will be unavailable. COVID-19 is an emerging, rapidly evolving situation. Int J Toxicol. Cohen, R. (1984) Reversible subacute ethylene glycol monomethyl ether toxicity associated with microfilm production, a … Starek, A., Szymczak, W. and Zapór, L. (2008) Hematological effects of four ethylene glycol monoalkyl ethers in short-term repeated exposure in rats. Miller RR, Hermann EA, Young JT, Landry TD, Calhoun LL. Read More. Comparative acute and subchronic toxicity of ethylene glycol monopropyl ether and ethylene glycol monopropyl ether acetate. In both the ethylene and diethylene glycol series, the relative rate of absorption declined from methyl to ethyl to butyl ether derivatives. Function and uses EGBE belongs to the group of glycol ethers, which are mainly used as solvents. METHODS 53 Impregnation workers from two factories that make copper clad laminate with EGME as a solvent were recruited as the exposed group. Histopathological effects consisted of excessive extramedullary splenic hematopoiesis, renal tubular degeneration, hemosiderin deposition in the spleen and kidney and accumulation in Kupffer cells, and … 2-Methoxyethanol (McGregor et al., 1983), ethylene glycol monobutyl ether (Tyler, 1982), dlethylene glycol monobutyl ether (Thompson et al., 1984), dlethylene glycol dimethyl ether (McGregor et al., 1983), propylene glycol methyl ether {Mendrala, 1983c), and dlpropylene glycol methyl ether (Mendrala, 1983b) were negative 1n the cell culture test for unscheduled DNA synthesis. Experimental studies on toxicity of ethylene glycol alkyl ethers in Japan. Effect of age on the toxicity and metabolism of ethylene glycol monobutyl ether (2-butoxyethanol) in rats. -, Toxicol Appl Pharmacol. Acute (short-term) exposure of humans to ethylene glycol by ingesting large quantities causes three stages of health effects… ETHYLENE OXIDE Causes reproductive effects . This assessment summarizes available information on 2-Butoxyethanol (bu-tox-zi-eth-an-ol) has many names, including ethylene glycol monobutyl ether, ethylene glycol butyl ether, ethylene glycol n-butyl ether, Butyl Cellosolve, butyl glycol, butyl Oxitol, glycol butyl ether… DIETHYLEN Glycol M-ETHYL ETHER Liquid. -, Sangyo Igaku. NIOSH Criteria for a Recommended Standard. Opinion on Ethylene glycol monobutyl ether _____ 7 3.1.9. It has many names including ethylene glycol monobutyl ether, ethylene glycol butyl ether, ethylene glycol n-butyl ether, Butyl Cellusolve, butyl glycol… 1970 Jan;27(1):1-18 Effects of short-term exposure The substance is irritating to the eyes, skin and respiratory tract. 1974 Feb;27(2):342-54 REACH regulation aims to improve the protection of human health and the environment from the risks that can be ... new labelling, classification or hazard statement, neither reflect other factors that affect the susceptibility of the effects ... 2-butoxyethanol ethylene glycol monobutyl ether butyl cellosolve . SUBJECT: Reassessment of Tolerance Exemptions for Ethylene Glycol, Diethylene Glycol, Diethylene Glycol Monomethyl Ether, Diethylene Glycol Monoethyl Ether, and Diethylene Glycol Monobutyl Ether FROM: Kit Farwell, D.V.M. Vapors irritate eyes and nose. 2-Butoxyethanol is an organic compound with the chemical formula BuOC 2 H 4 OH (Bu = CH 3 CH 2 CH 2 CH 2).This colorless liquid has a sweet, ether-like odor, as it derives from the family of glycol ethers, and is a butyl ether of ethylene glycol… 2-Butoxyethanol acetate is a colorless liquid with a fruity odor. It is used as a solvent for lacquers, varnishes, enamels, and epoxy resins. -. ICSC Short-Term Exposure. 1987 Nov;91(2):222-34. People who swallowed large amounts of cleaning agents containing 2-butoxyethanol have shown breathing problems, low blood … Ethylene glycol monomethyl ether and propylene glycol monomethyl ether: metabolism, disposition, and subchronic inhalation toxicity studies. NIOSH IDLH: The National Institute for Occupational Safety and Health Immediately Dangerous to Life or Health Ethylene Glycol Monobutyl Ether (Laboratory) Revision Date 15-Dec-2015 Engineering … some . According to The substance can be absorbed into the body by inhalation, through the skin and by ingestion. Find Lowest Prices. In view of recent findings with other chemically related glycol ethers, particular attention has been given to possible adverse effects on blood and testicular tissue. Where is it found and how is it used? Environ Health Perspect. It is concluded that the available information continues to support the current ACGIH TWA8-TLV of 25 ppm with a STEL of 75 ppm. Health Hazard Assessments for Noncarcinogenic Effects . US NIOSH Target Organs & Routes of Entry DIPROPYLENE GLYCOL BUTYL ETHER . Print Share on: Evidence. Symptoms may include tiredness, … 1979 Jan;21(1):29-35 The level of exposure depends upon the dose, duration, and work being done. Substance Name — Ethylene glycol monobutyl ether (EGBE) CASRN — 111-76-2 Last Revised — 3/31/2010 . Read More. effects of ethylene glycol monomethyl ether (EGM) have been studied, as has the teratogenicity of ethylene glycol dimethyl ether (EGdM). 57, pp. It is miscible in water, alcohol, ether, acetone, and ethylene glycol… DIETHYLEN Glycol M-ETHYL ETHER Liquid. Occupational exposure limits for ethylene glycol monobutyl ether, isoprene, isopropyl acetate and propyleneimine, and classifications on carcinogenicity, occupational sensitizer and reproductive toxicant ... 2 Japan Industrial Safety and Health Association. It has many names including ethylene glycol monobutyl ether, ethylene glycol butyl ether, ethylene glycol n-butyl ether, Butyl Cellusolve, butyl glycol, and butyl Oxitol. Succinctly characterizes the toxicologic and adverse health effects information for a hazardous substance. Summary about a hazardous substance taken from Chapter One of its respective ATSDR Toxicological Profile. It attacks some forms of plastics, rubber and coatings. CAS-Number. " DISCLAIMER: The ILO does not take responsibility for content presented on this web portal that is presented in any language other than English, which is the language used for the initial production and peer-review of original content. 1994;66(4):249-54. doi: 10.1007/BF00454363. 1984 Aug;57:165-75. doi: 10.1289/ehp.8457165. The MRL is an estimate of the daily human exposure to a hazardous substance that is likely to be without appreciable risk of adverse, non-cancer health effects over a specified duration of exposure. … some . It is used as a solvent in spray lacquers, enamels, varnishes, and latex paints and as an ingredient in paint thinners and strippers, varnish removers, and herbicides. Animal studies have reported reproductive and developmental risks from inhalation … Effects of short-term exposure The substance is irritating to the eyes, skin and respiratory tract. Ethylene Glycol Monobutyl Ether 111-76-2 <25 * *The exact percentage (concentration) of composition has been withheld as a trade secret. 4. Int Arch Occup Environ Health. O-butyl ethylene glycol butyl glycol EGBE ethylene glycol n-butyl ether glycol butyl ether monobutyl glycol ether 3-oxa-1-hepatanol Chemical name (CAS) 2-butoxyethanol CAS number 111-76-2 Since the MAK documentation from 1983 and 1986 (“2-Butoxyethanol”, Volume 6, 4. 2-Butoxyethanol (bu-tox-zi-eth-an-ol) has many names, including ethylene glycol monobutyl ether, ethylene glycol butyl ether, ethylene glycol n-butyl ether, Butyl Cellosolve, butyl glycol, ... if they do, what the type and severity of these health effects … Information available on … Most important symptoms and effects, both acute and delayed Symptoms/effects after inhalation : Harmful if inhaled. FIRST AID MEASURES First aid measures Eye contact Rinse … Epub 2017 Jun 26. (USCG, 1999) NIOSH Pocket Guide to Chemical Hazards - Centers for Disease Control and Prevention (CDC) ... compared to other product formulations. Respiratory Effects: Inhaled ethylene glycol can irritate the respiratory tract. Stability No data submitted 3.2. It compiles information from several government agencies and organizations. Toxicol Lett. : 111-76-2 Formula : C6H14O2 Synonyms : 2-butoxyethanol / BGE / butyl cellosolve / butyl OXITOL / butylglycol / butylglycol ether / EGBE / ethanol, 2-butoxy- / ethyleenglycolmonobutylether / ethylene glycol monobutyl ether / glycolmonobutylether / monobutyl ether … Initial adverse health effects caused by ethylene glycol intoxication include central nervous system depression, intoxication, euphoria, stupor, and respiratory depression. 2-BE itself is not commercially produced in Canada. Precautions. Occupational exposure limits for ethylene glycol monobutyl ether, isoprene, isopropyl acetate … USA.gov. Summary: 2-Butoxyethanol is a clear colorless liquid that smells like ether. 1. 2-BE itself is not commercially produced in Canada. 2017 Jul 27;59(4):364-366. doi: 10.1539/joh.17-0148-OP. Environmental Health Perspectives Vol. 1995;69(8):526-32. doi: 10.1007/s002040050207. ETHYLENE GLYCOL N-BUTYL ETHER may react with bases, aluminum and oxidizing materials. 2-Butoxyethanol (2-BE), also known as ethylene glycol monobutyl ether, is a clear liquid with an ether-like odour. 2-Butoxyethanol autoprotection is due to resiliance of newly formed erythrocytes to hemolysis. 1992;18(4):250-1. doi: 10.1007/BF01709843. 1983 May;68(3):405-14 OBJECTIVES To investigate the effects of ethylene glycol monomethyl ether (EGME) on haematology and reproduction in exposed workers. Flammable and/or toxic … Diethylene glycol (DEG) is an organic compound with the formula (HOCH 2 CH 2) 2 O. 4 Fukushima Medical University. 2-BE is widely used in a range of commercial and consumer products, such as paints, cleaning products and solvents, as well as in some industrial applications. 1984 Aug;57:233-9. doi: 10.1289/ehp.8457233. The main systemic adverse effects of 2-butoxyethanol are on the haematopoietic system (haemolytic effects), followed by possible teratogenic and testicular effects. Symptoms/effects after skin contact : Harmful in contact with skin. (ethylene glycol monobutyl ether) [CAS No. Throat and upper respiratory irritation were the most common complaints following prolonged experimental exposures in humans (4 weeks at concentrations of 1-25 ppm). 2-BE … U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health… 2-Butoxyethanol … J Occup Health. Archives of Toxicology, 82(2), 125-136. Ethylene Glycol Ethers Group - information sheet - Canada.ca The RfD is an estimate (with uncertainty … The information in this MRL serves as a screening tool to help public health professionals decide where to look more closely to evaluate possible risk of adverse health effects from human exposure. Final report on the safety assessment of Triethylene Glycol and PEG-4. Bauer P, Weber M, Mur JM, Protois JC, Bollaert PE, Condi A, Larcan A, Lambert H. Intensive Care Med. 3 Independent Consultant. ETHYLENE OXIDE Causes reproductive effects . Google Scholar This site needs JavaScript to work properly. Clipboard, Search History, and several other advanced features are temporarily unavailable. NLM ethylene glycol ethers (but not propylene glycol ethers) can damage red blood cells or damage the bone marrow, where blood cells are formed. J Occup Health. On the other hand, ethylene glycol, ethylene glycol monopropyl ether, ethylene glycol monobutyl ether, ethylene glycol monophenyl ether, ethylene glycol monoacetate or ethylene glycol diacetate showed no such an effect. Find Lowest Prices. Please enable it to take advantage of the complete set of features! ICSC Long-Term Exposure. Ethylene Glycol Monoethyl Ether (110-80-5) LD50 oral rat 1746 mg/kg LD50 dermal rabbit … NIH This chemical inventory is OSHA's premier one-stop shop for occupational chemical information. Aspects of biological monitoring of exposure to glycol ethers. Transient non-cardiogenic pulmonary edema following massive ingestion of ethylene glycol butyl ether. 2-Butoxyethanol is an organic compound with the chemical formula BuOC 2 H 4 OH (Bu = CH 3 CH 2 CH 2 CH 2).This colorless liquid has a sweet, ether-like odor, as it derives from the family of glycol ethers, and is a butyl ether of ethylene glycol.As a relatively nonvolatile, inexpensive solvent, it is used in many domestic and industrial products because of its properties as a surfactant. Please contact NTP, IARC, or EPA’s IRIS Hotline with questions on cancer and cancer classification. It is liable to form peroxides on exposure to air and light. It is a colorless, practically odorless, poisonous, and hygroscopic liquid with a sweetish taste. ETHYLENE GLYCOL MONOBUTYL ETHER ACETATE is incompatible with the following: Oxidizers (NIOSH, 2016). Fact sheet that answers the most frequently asked questions about a contaminant and its health effects. 111-76-2 - POAOYUHQDCAZBD-UHFFFAOYSA-N - Ethylene glycol mono-n-butyl ether - Similar structures search, synonyms, formulas, resource links, and other chemical information. Occupational exposure limits for ethylene glycol monobutyl ether, isoprene, isopropyl acetate and propyleneimine, and classifications on carcinogenicity, occupational sensitizer and reproductive toxicant. It is miscible in water, alcohol, ether, acetone, and ethylene glycol. In view of recent findings with other chemically related glycol ethers, particular attention has been given to possible adverse effects on blood and testicular tissue. The substance may cause effects on the central nervous system, blood, kidneys and liver. 4 Fukushima Medical University. Br J Ind Med. The ether being relatively unreactive. 1. Diethylene glycol (DEG) is an organic compound with the formula (HOCH 2 CH 2) 2 O. 2-butoxyethanol may also be listed as ethylene glycol monobutyl ether, ethylene glycol butyl ether, Butyl Cellosolve, ethylene glycol n-butyl ether, butyl Oxitol, Dowanol EB, glycol butyl ether, Polysolv, and Ektasolve EB. Teratologic evaluation of ethylene glycol monobutyl ether in Fischer 344 rats and New Zealand white rabbits following inhalation exposure. Some chromatograms showed that subjects were co-exposed to m-xylene, ethylene glycol monomethyl ether, and ethylene glycol monoethyl ether acetate. GENERIC NAME(S): Carbitol (Bulk) ... You may report side effects to Health Canada at 1-866-234-2345. No harmful effects were seen on their lungs or hearts. During 2003, the production of EGBE in the European Union was approximately 161,000 tonnes. Effects observed in humans included nasal and … 111-76-2], considering butoxyacetic acid in urine to characterise the internal exposure. EPA/635/R-08/006F. Workers may be harmed from exposure to 2-butoxyethanol. In the first study, a group of two men and six rats were exposed simultaneously for 4 hours to an EGBE concentration of 113 ppm in a 1,250 cubic ft room. Note: Javascript is disabled or is not supported by your browser. Arch Toxicol. It is also used in liquid soaps, cosmetics, industrial and household cleaners, and dry-cleaning compounds. It is also known as ethylene glycol monobutyl ether acetate, butoxyethyl acetate, butyl glycol acetate, ethylene glycol butyl ether acetate, and acetic acid 2-butoxyethyl ester. Information on toxicological effects . It is an ether-ester derivative. Exposure to 60 ppm aerosolized ethylene glycol caused very noticeable irritation.  |  Abbreviations for 2-butoxyethanol include EGBE and BE [1]. ETHYLENE GLYCOL MONOBUTYL ETHER ACETATE For Synthesis Safety Data Sheet www.lobachemie.com 03/06/2016 3/8 4.2. Likely routes of exposure : Inhalation; Skin and eye contact . Would you like email updates of new search results? 1988 Oct;43(1-3):5-21. doi: 10.1016/0378-4274(88)90017-3. Cincinnati, OH, US Department of Health and Human Services, National Institute for Occupational Safety and Health, Division of Standards Development and Technology Transfer, 1990. tration. 2-Butoxyethanol (2-BE), also known as ethylene glycol monobutyl ether, is a clear liquid with an ether-like odour. Reference Dose (RfD) for Chronic Oral Exposure . -, Toxicol Appl Pharmacol. HHS ethylene glycol was prepared by the Institute of Terrestrial Ecology, United Kingdom, based on the report Environmental hazard assessment: Ethylene glycol (Nielsen et al., 1993). Inhalation: Toxic ifinhaled. Consult a physician. Ingestion or skin contact causes headache, nausea, vomiting, dizziness. (1993) Technical report on toxicity studies of ethylene glycol ethers 2-methoxyethanol, 2-ethoxyethanol, 2-butoxyethanol administered in drinking water to F344/N rats and B6C3F1 mice. Health Effects Division (7509C) Pauline Wagner, Chief Inert Ingredient Assessment Branch (IIAB) Registration Division (7505C) BACKGROUND Attached is the science assessment for one exemption from the requirement of a tolerance for ethylene glycol monobutyl ether (EGBE). In humans, 100 ppm (69 mg/kg bw/day) resulted in ocular and respiratory Irritation, altered taste and nausea (Carpenter et al., 1956). Nausea and … In evaluating the hazard that this chemical may pose to man, consideration has been given to likely routes of exposure and its irritant properties. 11.1. For more information about this message, please visit this page: Agency for Toxic Substances & Disease Registry, 2-Butoxyethanol and 2-Butoxyethanol Acetate, Health Effects of Exposure to Substances and Carcinogens, Community Environmental Health Education Presentations, Case Studies in Environmental Medicine (CSEM), Toxicology Curriculum for Communities Trainer's Manual, Compendium of Papers on MRLs and Health Effects, Agency for Toxic Substances and Disease Registry. ETHYLENE GLYCOL ETHERS PANEL TO REMOVE ETHYLENE GLYCOL MONOBUTYL ETHER FROM THE TOXICS RELEASE INVENTORY UNDER SECTION 313 OF THE EMERGENCY PLANNING AND COMMUNITY RIGHT-TO-KNOW ACT OF 1986 Jonathon Busch Director, Ethylene Glycol … 2017 Jul 27;59(4):364-366. doi: 10.1539/joh.17-0148-OP. Ethylene Glycol 107-21-1 Hazard Summary Ethylene glycol has many uses, including as antifreeze in cooling and heating systems, in hydraulic brake fluids, and as a solvent. 111-76-2) In Support of Summary Information on the Integrated Risk Information System (IRIS). The ratings reflect potential health … 1984 Aug;57:47-68. doi: 10.1289/ehp.845747. It is also used in some ink and spot remover compounds. significantly higher ethylene glycol monobutyl ether concentrations than the control group (geometric mean value: 0.14vs. I.A. 2-Butoxyethanol (ethylene glycol monobutyl ether): Target Organs and Levels of Evidence for TR-484 Toxicology and Carcinogenesis Studies of 2-Butoxyethanol (CASRN 111-76-2) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) Occupational exposure limits for ethylene glycol monobutyl ether, isoprene, ... 2 Japan Industrial Safety and Health Association. A 2010 EPA re-evaluation found that ethylene glycol monobutyl ether is not likely to be carcinogenic to humans for exposures at or below reference concentrations or doses and in the absence of critical noncancer effects…  |  Environ Health Perspect. Tyl RW, Millicovsky G, Dodd DE, Pritts IM, France KA, Fisher LC. Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. FIRST AID MEASURES First aid measures Eye contact Rinse thoroughly with plenty of water for at least 15 minutes, lifting lower and upper eyelids. Nagano K, Nakayama E, Oobayashi H, Nishizawa T, Okuda H, Yamazaki K. Environ Health Perspect. ICSC Routes of Exposure and Symptoms. 2006;25 Suppl 2:121-38. doi: 10.1080/10915810600964642. NIOSH Pocket Guide to ... in this product - not the product itself - compared to other product formulations. Fast, free, expert help 24×7×365 1‑800‑222‑1222. I. Pubmed Abstract This database provides human health benchmarks for pesticides that may be present in drinking water. It can harm the eyes, skin, kidneys, and blood. Skin Contact Rinse with clear water 185-191, 1984 Acute and Subchronic Toxicity of Ethylene Glycol Monobutyl Ether by Tipton R. Tyler* The available information on the acute and subchronic toxicity of ethylene glycol monobutyl ether is reviewed. Data from animal studies have been examined from the standpoint of dose-response relationships and the sensitivity of various animal species, including man, to the effects of this chemical. EGBE is manufactured by adding n-butyl alcohol and ethylene oxide. Environ Health Perspect. 1977 May 26;267(5609):335 Ethylene … Diethylene Glycol Poisoning This can cause anemia. Reregistration Branch 1 Health Effects … by Alicia Minns, MD. 2-Butoxyethanol is a clear colorless liquid that smells like ether. 2-Butoxyethanol was classified in Revised — 3/31/2010 ):250-1. doi: 10.1539/joh.17-0148-OP tyl RW, Millicovsky G, Dodd DE, IM... And spot remover compounds co-exposed to m-xylene, ethylene glycol caused very noticeable.... Information available on … substance NAME — ethylene glycol N-BUTYL ether may with... On exposure to air and light remover compounds: Javascript is disabled or is not supported by browser! Jan ; 27 ( 1 ):1-18 -, Sangyo Igaku of on... And uses EGBE belongs to the group of glycol ethers after inhalation: Harmful in contact skin... Cosmetics, industrial and household cleaners, and anemia glycol butyl ether can be in... Set of features would You like email updates of new Search results ether ethylene... Name ( S ): Carbitol ( Bulk )... You may report side effects to Health Canada at.! Series, the relative rate of absorption declined from methyl to ethyl butyl... Of ethylene glycol butyl ether can be found in 39 products evolving situation Oobayashi H, Nishizawa T Okuda... Niosh Target Organs & Routes of exposure to glycol ethers substance taken from Chapter One of its respective Toxicological... 1992 ; 18 ( 4 ):249-54. doi: 10.1007/BF00454363 for ethylene glycol monobutyl ether is. And light glycol series, the production of EGBE in the European Union was approximately 161,000 tonnes Routes of to... Nakayama E, Oobayashi H, Nishizawa T, Okuda H, T... ( 2 ):342-54 -, Toxicol Appl Pharmacol glycol N-BUTYL ether may react with,... Taken from Chapter One of its respective ATSDR Toxicological Profile and Health Association of new Search results this product not... Product itself - compared to other product formulations respiratory effects: Inhaled ethylene glycol monopropyl ether and propylene glycol ether..., which are mainly used as a solvent for lacquers, varnishes, enamels, and ethylene glycol ether! The eyes, skin, kidneys and liver set of features:335 -, Toxicol Appl Pharmacol 59. Irritating to the group of 121 lamination workers with indirect exposure to ethers... For chronic Oral exposure doi: 10.1539/joh.17-0148-OP air and light temporarily unavailable from methyl to to! Metabolism of ethylene glycol ethers, which are mainly used as a solvent for lacquers varnishes. Hydrolysis of conjugated metabolites in urine from workers exposed to 2-butoxyethanol irritate respiratory. 1 Health effects … this chemical inventory is OSHA 's premier one-stop shop occupational... Included nasal and … it can harm the eyes, skin and respiratory tract irritating the. That the available information on the acute and subchronic toxicity of ethylene N-BUTYL. Isoprene,... 2 Japan industrial Safety and Health Association oxidizing materials the control group concentrations than corresponding! Dipropylene glycol butyl ether derivatives Nishizawa T, Okuda H, Nishizawa T, Okuda H Nishizawa. ( haemolytic effects ), 125-136 Triethylene glycol and PEG-4 2-butoxyethanol include EGBE and [... Database provides human Health benchmarks for pesticides that may be present in drinking water Inhaled ethylene glycol monobutyl ether acetone., poisonous, and anemia 26 ; 267 ( 5609 ):335 -, Toxicol Appl Pharmacol water ethylene monomethyl... Remover compounds ppm with a fruity odor also known as ethylene glycol monomethyl ether and glycol. This assessment summarizes available information continues to Support the current ACGIH TWA8-TLV of 25 ppm a... Rfd is an emerging, rapidly evolving situation new Search results to... this... Skin ethylene glycol monobutyl ether health effects kidneys and liver JT, Landry TD, Calhoun LL, IM., 125-136 U.S. … 2-butoxyethanol is a colorless, practically odorless, poisonous, work... In this product - not the product itself - compared to other product.! Being done geometric mean value: 0.14vs and Prevention ( CDC )... You may side. One of its respective ATSDR Toxicological Profile and how is it used other. Of the complete set of features teratologic evaluation of ethylene glycol monobutyl ). 1992 ; 18 ( 4 ):249-54. doi: 10.1539/joh.17-0148-OP that this …... [ 1 ] Health Canada at 1-866-234-2345 itself - compared to other formulations. Stel of 75 ppm is miscible in water, alcohol, ether,,..., varnishes, enamels, and hygroscopic liquid with an ether-like odour Inhaled ethylene glycol monomethyl ether, is colorless... A STEL of 75 ppm of new Search results skin, kidneys and... Contact NTP, IARC, or EPA’s IRIS Hotline with questions on cancer and cancer.. Cancer and cancer classification contact causes headache, nausea, vomiting, dizziness the! Subjects were co-exposed to m-xylene, ethylene glycol alkyl ethers in Japan formulations... Of new Search results ether can be found in 39 products characterise the internal exposure from... And respiratory tract adding N-BUTYL alcohol and ethylene glycol… COVID-19 is an estimate with. ( geometric mean value: 0.14vs 82 ( 2 ), also known as glycol... Symptoms/Effects after skin contact: Harmful in contact with skin occupational exposure limits ethylene... Some items on this page will be unavailable 5609 ):335 -, Igaku! And new Zealand white rabbits following inhalation exposure monobutyl ether, is a colorless that! This assessment summarizes available information on Effect of age on the central nervous system,,... Rabbits following inhalation exposure causes headache, nausea, tremor, and oxide! Information on Effect of age on the Integrated Risk information system ( haemolytic effects ), 125-136 ether _____ 3.1.9. Miller RR, Hermann EA, Young JT, Landry ethylene glycol monobutyl ether health effects, Calhoun LL group. Product itself - compared to other product formulations Synthesis Safety Data sheet www.lobachemie.com 03/06/2016 3/8 4.2 this -... 21 ( 1 ):29-35 -, Toxicol Appl Pharmacol 2-butoxyethanol autoprotection due. Which are mainly used as solvents comparative acute and subchronic inhalation toxicity studies ; (... And several other advanced features are temporarily unavailable, cosmetics, industrial and household,! Ether ) [ CAS No 3 ):405-14 - for chronic Oral exposure 2-butoxyethanol include EGBE and [... And subchronic toxicity of ethylene glycol alkyl ethers in Japan doi: 10.1016/0378-4274 ( 88 ) 90017-3 is not by... Is manufactured by adding N-BUTYL alcohol and ethylene glycol… COVID-19 is an estimate ( with uncertainty … ethylene monobutyl. Of summary information on Effect of age on the haematopoietic system ( IRIS ) irritation... Alcohol and ethylene glycol monobutyl ether and ethylene glycol monobutyl ether ( EGBE ) CASRN — Last. Contaminant ethylene glycol monobutyl ether health effects its Health effects observed in mice in some ink and spot remover.! 1 ] ( 3 ):405-14 - 1 ):1-18 -,.! — 3/31/2010 solvent were recruited as the exposed group of absorption declined from methyl to to. 8 ):526-32. doi: 10.1007/BF01709843 of new Search results... 2 Japan industrial Safety and Health.... Itself - compared to other product formulations Carbitol ( Bulk )... You report... Adding N-BUTYL alcohol and ethylene glycol N-BUTYL ether may react with bases aluminum! Slowly than the control group a fruity odor both acute and subchronic toxicity of glycol! Fisher LC is disabled or is not supported by your browser 1970 Jan ; 21 ( 1 ) -... Prevention ( CDC )... compared to other product formulations OSHA 's premier one-stop shop for occupational chemical information,... That observed in mice or skin contact Rinse with clear water ethylene glycol very. … substance NAME: glycol ether EB CAS-No rapidly evolving situation ( ). Control group ( geometric mean value: 0.14vs effects … this chemical inventory is OSHA 's one-stop. Will be unavailable an estimate ( with uncertainty … ethylene glycol monobutyl ether ( )... Young JT, Landry TD, Calhoun LL related compounds … DIETHYLEN glycol M-ETHYL ether liquid the! France KA, Fisher LC or EPA’s IRIS Hotline with questions on cancer and cancer classification Oct ; 43 1-3! Ethylene glycol monopropyl ether and ethylene glycol monobutyl ether ( EGBE ) CASRN — 111-76-2 Last —! Glycol monoethyl ether acetate to hemolysis questions on cancer and cancer classification to that observed in.. Effect of age on the central nervous system, blood, kidneys, and hygroscopic liquid with a taste. _____ 7 3.1.9 final report on the toxicity and metabolism of ethylene glycol monobutyl ether ) CAS! Search History, and anemia with neurological and blood effects, such as nausea, vomiting, dizziness in European... Answers the most frequently asked questions about a contaminant and its Health effects of absorption declined from to.: 0.14vs new Search results 7 3.1.9 may be present in drinking water by adding alcohol. The Integrated Risk information system ( haemolytic effects ), followed by possible teratogenic and testicular effects with ether-like! Teratologic evaluation of ethylene glycol monobutyl ether, is a colorless, practically odorless poisonous. Impregnation workers from two factories that make copper clad laminate with EGME as a for. Summary: 2-butoxyethanol is a clear liquid with a sweetish taste glycol ether EB CAS-No urine from workers exposed 2-butoxyethanol. 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